Neurodegenerative diseases, Amyotrophic Lateral Sclerosis (ALS), motor neurons, neuroinflammation, microglia, macrophages, iPS cells, genetics

Team research topics:

Neurodegenerative diseases, Amyotrophic lateral, Amyotrophic Lateral Sclerosis (ALS), motor neurons, neuroinflammation, microglia, macrophages, iPS cells, genetics.

 

Main techniques used :

• Cell culture: primary mouse microglia, primary mouse macrophages, motor neurons and microglia/macrophages derived from human IPS, human macrophages, human fibroblasts, lymphoblasts, human and murine cell lines

• Transcriptomics (RNAseq)

• Laser microdissection

• Immunohistochemistry, immunofluorescence, western blot, immunoprecipitation

• Analysis of motor behavior in mice

Address :
Hôpital Pitié-Salpêtrière 47 bd de l’Hôpital 75013 Paris

Team leader :
Severine Boillee
Name of co-team leader :

Administrative Contact Name :


Website : Cliquez ici
Key words : Sclérose Latérale Amyotrophique (SLA), motoneurones, neuroinflammation, cellules iPS, génétique Amyotrophic Lateral Sclerosis (ALS), motor neurons, neuroinflammation, iPS cells, genetics