Memory, Oscillations and Brain states
ESPCI-UMR 8249
Axe 2 : Approches quantitatives à l'exploration du comportement et de la cognition
Axe 3 : Réseaux neuronaux, modélisation et intelligence artificielle
Team research topics:
The MOBs team aims to investigate the interaction between brain and body and their role in memory processing and emotion through in vivo and ex-vivo approaches coupling behavioral tasks, extracellular electrophysiology, optogenetics and brain-computer interface.
Building on prior research on theta oscillations and hippocampal sharp-waves ripples in memory and sleep, the team showed that false memories can be created during sleep by using a brain-computer interface and real-time detection of spontaneous neuronal reactivation.
Recently the team developed a new axis of research on the influence of brain-body interaction in emotion. The team showed in mice that during fear-induced freezing, the olfactory bulb transmits regular breathing rhythm to the prefrontal cortex, playing a specific role in freezing maintenance. T present research of the team work on the distinction between fear/panic and anxiety, that could lead to efficient translational studies on neuropsychiatric disorders.
Main techniques used:
In vivo and ex-vivo approaches, behavioral tasks, extracellular electrophysiology, optogenetics and brain-computer interface.
ESPCI-CNRS 10 rue Vauquelin 75005 Paris
Team leader :
Karim Benchenane
Name of co-team leader :
Administrative Contact Name :
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Key words : #Peur #anxiété #sommeil #mémoire #interactions #corps-cerveau #interface #cerveau-machine #Fear #anxiety #sleep #memory #body-brain #interactions #brain-machine #interface