Retinal development and repair : use of pluripotent stem cells

Team research topics:

Our team is at the forefront of the development of cell-based therapies to tackle degenerative diseases of the retina, such as hereditary retinal dystrophies and age-related macular degeneration (AMD). We focus on basic and translational research using human induced pluripotent stem (iPS) cells to create 3D retinal avatars, called retinal organoids, by recapitulating human retinogenesis.

The aims of our laboratory are to use these organoid models to gain a better understanding of the cellular and molecular events that occur during human retinal development, and to generate retinal cells and tissues that can be used for modelling retinal diseases and developing different types of cell therapy.

Research Aeras:

• Pluripotent stem cells
• Organoids
• Cell therapy
• Disease Modeling

Main techniques used:

Stem cells, organoids, transplantation - disease modeling, visual restoration, screening.

Address :
17 Rue Moreau, 75012, Paris

Team leader :
Olivier Goureau
Name of co-team leader :

Administrative Contact Name :
Dominique Santiard-Baron

Website : Cliquez ici
Key words : #Organoïdes #Cellules #iPS #Vision #Rétine #Photorécepteur #Thérapie #cellulaire #Organoids #iPS #cells #Vision #Retina #Photoreceptor #Cell #therapy