Cerebral Imaging and Engineering Laboratory

The blood-brain barrier (BBB) remains the bottleneck for pharmacological therapy of neurological diseases, costing billionsto our societies.The goal of our team isto provide new solutionsto deliver drugsto the brain in a safe way in order to increase their efficacy on the target.Transcranial focused ultrasound is a particularly promising technique to transiently and locally disrupt thisvascular barrier. Since 2010,we use neuroimaging to characterize the technology and to develop translational strategies. We now aim at making it a reality for the highest possible number of patients in the future years.

the global scientific strategy of CIEL consists in building a framework of imaging technologies that are increasing the comprehension of fundamental mechanisms underlying brain functioning, but also in producing new diagnostic and therapeutic tools in a pathological context such as brain tumor, stroke, neurodegenerative and psychiatric diseases.

Address :
Centre d'études de Saclay, Bâtiment 145, 91191 Gif-sur-Yvette

Team leader :
MERIAUX Sébastien
Name of co-team leader :

Administrative Contact Name :


Website : Cliquez ici
Key words : metabolism#neuronal activity#molecular transport#ultrasound#MRI scanners#electrophysiology#animal models#