role of glutamatergic co-transmission

Our team seeks to understand the role of this co-transmission in normal and pathological brain function in mammals. Using behavioural biology, molecular biology, anatomy, microscopy and chemistry approaches, we are studying:

• The role of glutamatergic co-transmission in the establishment and maintenance of memories in mice
• The functional and behavioural consequences of variants identified in humans and their links with susceptibility to stress and the development of psychiatric pathologies 
• Characterisation of the networks expressing VGLUT3 and their role in the regulation of anxiety and vigilance states
• Differential expression of vesicular transporters in these bilingual neurons by developing high resolution microscopy approaches (STED, STORM)
• We are developing new ligands to control the expression and function of VGLUTs

Address :
Cassan, Bat. A, Campus Pierre et Marie Curie 7-9 quai Saint Bernard 75005 Paris

Team leader :
DAUMAS Stéphanie
Name of co-team leader :
PIETRANCOSTA Nicolas
Administrative Contact Name :
Alix Rousselet

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