Team research topics:

Cellular movement is ubiquitous in the development of the nervous system: neurons migrate towards their final destination, and their axons navigate towards their target cells. The study of these processes has so far focused on the chemical signals that guide neuronal migration and axon growth. However, these movements are also influenced by mechanical forces, the function of which remains largely unknown in vivo.

In the laboratory, we are exploring this novel question using the zebrafish olfactory sensory circuit as a model.

 

Main techniques used:

Quantitative imaging on live embryos, measurement and perturbation of mechanical forces, genetic tools, drugs.

Address :
Campus Pierre et Marie Curie 7-9 quai Saint Bernard 75005 Paris

Team leader :
Marie Breau
Name of co-team leader :

Administrative Contact Name :


Website : Cliquez ici
Key words : #Développement #neuronal #morphogenèse #axone #forces #mécaniques #poisson #zèbre #Neuronal #development #morphogenesis #axon #mechanical #forces #zebrafish