Neural coding and vision restoration

Team research topics:

Our group studies retinal information processing in normal and pathological conditions and investigates how pathological conditions can be prevented. We also develop and test new therapeutic vision restoration strategies.

Our past and current work has investigated cell and animal models of different retinal diseases with either photoreceptor degeneration (retinitis pigmentosa, Usher syndrome) or neuronal loss (diabetic retinopathy or glaucoma). We have investigated different neuroprotective mechanisms including light filters, calcium channel blockers, taurine, VEGF, etc, and assessed new techniques for visual restoration such as optogenetic therapy targeting different cellular levels or prostheses using innovative structures and materials like diamond and graphene.

Research areas

• Retinal encoding of visual information
• Light toxicity on photoreceptors and retinal neurons
• Neuroproction on photoreceptors and retinal neurons
• New concepts of neuroprostheses for vision restoration
• Functional validation of optogenetic therapy for visual restoration

Main techniques used: 

Address :
17 Rue Moreau, 75012, Paris

Team leader :
Olivier Marre
Name of co-team leader :

Administrative Contact Name :
Dominique Santiard-Baron

Website : Cliquez ici
Key words : #modélisation #computationnelle #électrophysiologie #optogénétique #codage #visuel #circuit #rétinien #computational #modeling #electrophysiology #optogenetics #visual #coding #retinal