Team research topics:

Multiciliated ependymal cells possess dozens of motile cilia, the beating of which is crucial for the circulation of cerebrospinal fluid in the cerebral ventricles. These cells are strategically located at the interface between the ventricles and the parenchyma. Their unique morphology and functions strongly suggest that defects in the generation of these cells may be associated with a variety neurological disorders. Our team is studying their development using the mouse brain as a model system.

 

Main techniques used:

Genetics, immunolabeling, histology, electron and fluorescent microscopy, cell culture, biochemistry, molecular biology.

Address :
46 Rue d'Ulm, 75005, Paris

Team leader :
Nathalie Spassky
Name of co-team leader :

Administrative Contact Name :


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Key words : #cil #cellule #souche #neurale #cellule #épendymaire #plexus #choroide #liquide #céphalo-rachidien #cilia #neural #stem #cell #ependymal #cell #choroid #plexus #cerebrospinal #fluid