NeuroInfection & Immunité
NeuroPSI
Axe 1 : Génomique, cellules humaines, reprogrammation et neuro-organoïdes
Zebrafish as an animal model; live imaging; genome editing; behavioral testing; transcriptomics
We study interactions between the innate immune system and the developing nervous system. In particular, we analyze the outcomes of viral encephalitis, distinguishing the impact of infection itself and of induced neuroinflammation, with the long-term goal of mitigating sequelae. We also study how sterile inflammation perturbs differentiation of some neuronal subtypes, such as dopaminergic neurons, promoting late onset of psychiatric diseases; or how it impacts brain repair.
Address :
Institut des Neurosciences Paris-Saclay (NeuroPSI) Université Paris-Saclay / CNRS Centre CEA Paris-Saclay - Bât. 151 91400 Saclay, France
Team leader :
Jean-Pierre Levraud
Name of co-team leader :
Administrative Contact Name :
Website : Cliquez ici
Key words : #Poisson-zèbre #neuroinflammation #interféron #développement #dopamine #Zebrafish #neuroinflammation #interferon #development #dopamine
Institut des Neurosciences Paris-Saclay (NeuroPSI) Université Paris-Saclay / CNRS Centre CEA Paris-Saclay - Bât. 151 91400 Saclay, France
Team leader :
Jean-Pierre Levraud
Name of co-team leader :
Administrative Contact Name :
Website : Cliquez ici
Key words : #Poisson-zèbre #neuroinflammation #interféron #développement #dopamine #Zebrafish #neuroinflammation #interferon #development #dopamine