Neurogenesis and circuit development
IdV
Axe 1 : Génomique, cellules humaines, reprogrammation et neuro-organoïdes
Axe 3 : Réseaux neuronaux, modélisation et intelligence artificielle
Team research topics:
Our team studies how the neurons that compose the circuits of the central nervous system develop from embryonic neural stem cells. We focus on two complementary models, the cerebral cortex and the retina, where we seek to understand how neural stem cells generate different types of neurons and how their lineage influences circuit organization.
Main techniques used:
To track circuit development at the single cell level, we use transgenic approaches such as Brainbow, a technique that distributes fluorescent proteins of distinct colors among neural cells. These colors enable us to trace the lineage of neural stem cells and identify their clonal progeny, and to trace nerve cell processes (axons, dendrites) in circuit mapping efforts.
17 Rue Moreau, 75012, Paris
Team leader :
Jean Livet
Name of co-team leader :
Administrative Contact Name :
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Key words : #Neurodéveloppement #cellules #souches #neurales #lignage #cellulaire #Brainbow #Neurodevelopment #neural #stem #cells #cell #lineage